Email this article Synthesis and characterization of some novel 7-(aryl)-3-phenyl-6-(1H-tetrazol-5-yl)-5H-thiazolo[3,2-a]pyrimidin-5-one derivatives
- Authors: Khalifa N.M.1,2, Al-Omar M.A.1, Amr A.E.1,3
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Affiliations:
- Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy
- Department of Therapeutical Chemistry, Pharmaceutical and Drug Industries Division
- Applied Organic Chemistry Department
- Issue: Vol 87, No 7 (2017)
- Pages: 1618-1620
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/220868
- DOI: https://doi.org/10.1134/S1070363217070271
- ID: 220868
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Abstract
A series of novel tetrazole derivatives containing fused thiazolo[3,2-a]pyrimidines were synthesized in a one-pot three-component reaction of 7-(aryl)-5-oxo-3-phenyl-5H-thiazolo[3,2-a]pyrimidine-6-carbonitriles with sodium azide and ammonium chloride.
Keywords
About the authors
N. M. Khalifa
Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy; Department of Therapeutical Chemistry, Pharmaceutical and Drug Industries Division
Author for correspondence.
Email: nagykhalifa@hotmail.com
Saudi Arabia, Riyadh, 11451; Cairo, 12622
M. A. Al-Omar
Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy
Email: nagykhalifa@hotmail.com
Saudi Arabia, Riyadh, 11451
A. E. Amr
Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy; Applied Organic Chemistry Department
Email: nagykhalifa@hotmail.com
Saudi Arabia, Riyadh, 11451; Cairo, 12622
