Synthesis of 3-(4-fluorophenyl)-3-(4-methoxyphenyl)-1-propanarylamines and their antibacterial activity
- Authors: Arutyunyan N.S.1, Akopyan L.A.1, Akopyan R.A.1, Stepanyan G.M.1, Panosyan G.A.2, Gevorgyan G.A.1
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Affiliations:
- Mnjoyan Institute of Fine Organic Chemistry
- Molecular Structure Research Center
- Issue: Vol 87, No 6 (2017)
- Pages: 1300-1304
- Section: Letters to the Editor
- URL: https://journals.rcsi.science/1070-3632/article/view/220415
- DOI: https://doi.org/10.1134/S1070363217060275
- ID: 220415
Cite item
Abstract
Condensation of 3-(4-fluorophenyl)-3-(4-methoxyphenyl)-1-propanamine with aromatic aldehydes and ketones followed by the reduction of the obtained azomethines with NaBH4 afforded secondary propanaryl -amines, whose oxalates and hydrochlorides possess high antibacterial activity.
About the authors
N. S. Arutyunyan
Mnjoyan Institute of Fine Organic Chemistry
Email: gyulgev@gmail.com
Armenia, Azatutyan pr. 26, Yerevan, 0014
L. A. Akopyan
Mnjoyan Institute of Fine Organic Chemistry
Email: gyulgev@gmail.com
Armenia, Azatutyan pr. 26, Yerevan, 0014
R. A. Akopyan
Mnjoyan Institute of Fine Organic Chemistry
Email: gyulgev@gmail.com
Armenia, Azatutyan pr. 26, Yerevan, 0014
G. M. Stepanyan
Mnjoyan Institute of Fine Organic Chemistry
Email: gyulgev@gmail.com
Armenia, Azatutyan pr. 26, Yerevan, 0014
G. A. Panosyan
Molecular Structure Research Center
Email: gyulgev@gmail.com
Armenia, Yerevan
G. A. Gevorgyan
Mnjoyan Institute of Fine Organic Chemistry
Author for correspondence.
Email: gyulgev@gmail.com
Armenia, Azatutyan pr. 26, Yerevan, 0014
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