NO2-Fe(III)PcCl@C -catalyzed one-pot synthesis of tetrahydropyridine derivatives
- Authors: Wang J.1, Lin Q.1, Qiu J.1, Gou X.1, Hua C.1, Zhao J.1, Chen B.1
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Affiliations:
- Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, College of Chemistry and Materials Science
- Issue: Vol 87, No 4 (2017)
- Pages: 821-828
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/219397
- DOI: https://doi.org/10.1134/S1070363217040259
- ID: 219397
Cite item
Abstract
A highly efficient, one-pot synthesis of functionalized tetrahydropyridines by multicomponent condensation of ethyl acetoacetate, two equivalents of aromatic aldehyde, and aromatic amine in the presence of a catalytic amount of NO2-Fe(III)PcCl@C is reported. In this way, a series of pharmacologically interesting substituted pyridine derivatives were obtained in moderate to good yields.
About the authors
Jiao-dan Wang
Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, College of Chemistry and Materials Science
Email: chenbang@china.com.cn
China, Shaanxi, Xi’an 710069
Qiao-li Lin
Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, College of Chemistry and Materials Science
Email: chenbang@china.com.cn
China, Shaanxi, Xi’an 710069
Jun Qiu
Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, College of Chemistry and Materials Science
Email: chenbang@china.com.cn
China, Shaanxi, Xi’an 710069
Xiao-feng Gou
Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, College of Chemistry and Materials Science
Email: chenbang@china.com.cn
China, Shaanxi, Xi’an 710069
Cheng-wen Hua
Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, College of Chemistry and Materials Science
Email: chenbang@china.com.cn
China, Shaanxi, Xi’an 710069
Jun-long Zhao
Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, College of Chemistry and Materials Science
Email: chenbang@china.com.cn
China, Shaanxi, Xi’an 710069
Bang Chen
Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, College of Chemistry and Materials Science
Author for correspondence.
Email: chenbang@china.com.cn
China, Shaanxi, Xi’an 710069