Email this article Synthesis of some novel 2-thioxoimidazolidin-4-one substituted glycosyl hydrazone derivatives
- Authors: Khalifa N.M.1,2, Al-Omar M.A.1, Sediek A.A.3,4, Amr A.E.1,3
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Affiliations:
- Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy
- Department of Therapeutical Chemistry, Pharmaceutical and Drug Industries Division
- Chemical Industries Division
- Chemistry Department, Faculty of Sciences and Arts, Al-Kamil Branch
- Issue: Vol 87, No 3 (2017)
- Pages: 523-529
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/218888
- DOI: https://doi.org/10.1134/S1070363217039239
- ID: 218888
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Abstract
A series of novel 2-thioxoimidazolidine glycosides were prepared via reaction of the key intermediate 2-(benzylsulfanyl)-5-[4-(3-hydroxypropoxy)-3-(methoxybenzylidene)]-3-phenyl-1H-imidazol-4-one with different sugar aldose or sugar hydrazones to give the corresponding glycosides. The newly synthesized compounds were confirmed by physical and spectral data.
About the authors
N. M. Khalifa
Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy; Department of Therapeutical Chemistry, Pharmaceutical and Drug Industries Division
Author for correspondence.
Email: nagykhalifa@hotmail.com
Saudi Arabia, Riyadh, 11451; Dokki, Cairo, 12622
M. A. Al-Omar
Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy
Email: nagykhalifa@hotmail.com
Saudi Arabia, Riyadh, 11451
A. A. Sediek
Chemical Industries Division; Chemistry Department, Faculty of Sciences and Arts, Al-Kamil Branch
Email: nagykhalifa@hotmail.com
Egypt, Dokki, Cairo, 12622; Jeddah
A. E. Amr
Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy; Chemical Industries Division
Email: nagykhalifa@hotmail.com
Saudi Arabia, Riyadh, 11451; Dokki, Cairo, 12622
