Conventional and microwave-assisted synthesis of quinolone carboxylic acid derivatives
- Authors: Mirzaie Y.1, Lari J.1, Vahedi H.1, Hakimi M.1
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Affiliations:
- Department of Chemistry
- Issue: Vol 86, No 12 (2016)
- Pages: 2865-2869
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/217105
- DOI: https://doi.org/10.1134/S1070363216120525
- ID: 217105
Cite item
Abstract
Various antibacterial fluoroquinolone compounds are synthesized by the direct amination of 7-halo-6-fluoroquinolone-3-carboxylic acids with a variety of piperazine derivatives and (4aR,7aR)-octahydro-1H-pyrrolo[3,4-b]pyridine using microwave under different reaction conditions. Solvent free high yield microwave synthesis of antibacterial fluoroquinolone compounds is convenient, rapid and environmentally friendly method.
About the authors
Y. Mirzaie
Department of Chemistry
Author for correspondence.
Email: msc.mirzaee@gmail.com
Iran, Islamic Republic of, Tehran
J. Lari
Department of Chemistry
Email: msc.mirzaee@gmail.com
Iran, Islamic Republic of, Tehran
H. Vahedi
Department of Chemistry
Email: msc.mirzaee@gmail.com
Iran, Islamic Republic of, Tehran
M. Hakimi
Department of Chemistry
Email: msc.mirzaee@gmail.com
Iran, Islamic Republic of, Tehran