Synthesis and antimicrobial evaluation of substituted (1,1'-biphenyl)-4-yl(3-methylbenzofuran-2-yl)methanones by Suzuki cross-coupling reaction

Abstract

A series of new substituted [1,1'-biphenyl]-4-yl(3-methylbenzofuran-2-yl)methanones was prepared by Suzuki cross-coupling from (4-bromophenyl)(3-methylbenzofuran-2-yl)methanone. The obtained compounds were assayed for their in vitro antibacterial activity against different types of bacterial strains; antifungal activity was also examined by inhibitory effect against different fungal strains.