Email this article Synthesis and antimicrobial activity of N,6-diaryl-4-methyl-2-thioxo-1,2,3,6-tetrahydropyrimidine-5-carboxamides
- Authors: Gein V.L.1, Zamaraeva T.M.1, Balandina A.V.1, Dmitriev M.V.2
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Affiliations:
- Perm State Pharmaceutical Academy
- Perm State National Research University
- Issue: Vol 86, No 12 (2016)
- Pages: 2666-2670
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/216724
- DOI: https://doi.org/10.1134/S107036321612015X
- ID: 216724
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Abstract
Three-component reactions of acetoacetic acid N-arylamides, aromatic aldehydes, and thiourea afforded N,6-diaryl-4-methyl-2-thioxo-1,2,3,6-tetrahydropyrimidine-5-carboxamides. Structure and antimicrobial activity of the compounds obtained were examined.
About the authors
V. L. Gein
Perm State Pharmaceutical Academy
Author for correspondence.
Email: geinvl48@mail.ru
Russian Federation, ul. Polevaya 2, Perm, 614990
T. M. Zamaraeva
Perm State Pharmaceutical Academy
Email: geinvl48@mail.ru
Russian Federation, ul. Polevaya 2, Perm, 614990
A. V. Balandina
Perm State Pharmaceutical Academy
Email: geinvl48@mail.ru
Russian Federation, ul. Polevaya 2, Perm, 614990
M. V. Dmitriev
Perm State National Research University
Email: geinvl48@mail.ru
Russian Federation, Perm
