Synthesis of chemical compounds of chitosan with betulin under nearly homogeneous conditions
- Authors: Fedoseeva E.N.1, Ur’yash V.F.1, Kokurina N.Y.1, Fedoseev V.B.1,2
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Affiliations:
- Research Institute of Chemistry
- Razuvaev Institute of Organometallic Chemistry
- Issue: Vol 86, No 11 (2016)
- Pages: 2534-2540
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/216590
- DOI: https://doi.org/10.1134/S1070363216110219
- ID: 216590
Cite item
Abstract
Chemical compounds of chitosan with betulin have been synthesized with the use of chitosan gels in alcoholic and acetic acid dispersions under nearly homogeneous conditions. The resulting biphilic compounds contain up to one betulin residue per 2–3 chitosan units. The formation of chemical compounds of chitosan with betulin has been confirmed by several physicochemical methods. The procedure developed for the preparation of chitosan gels with alcohol-containing dispersion medium makes it possible to carry out chitosan reactions with compounds poorly soluble in aqueous and acetic acid media.
About the authors
E. N. Fedoseeva
Research Institute of Chemistry
Author for correspondence.
Email: el.nik.fedoseeva@gmail.com
Russian Federation, pr. Gagarina 23, Nizhny Novgorod, 603950
V. F. Ur’yash
Research Institute of Chemistry
Email: el.nik.fedoseeva@gmail.com
Russian Federation, pr. Gagarina 23, Nizhny Novgorod, 603950
N. Yu. Kokurina
Research Institute of Chemistry
Email: el.nik.fedoseeva@gmail.com
Russian Federation, pr. Gagarina 23, Nizhny Novgorod, 603950
V. B. Fedoseev
Research Institute of Chemistry; Razuvaev Institute of Organometallic Chemistry
Email: el.nik.fedoseeva@gmail.com
Russian Federation, pr. Gagarina 23, Nizhny Novgorod, 603950; ul. Tropinina 49, Nizhny Novgorod, 603137