Synthesis of 1,3,4,6-tetraoxo compounds
- Authors: Mukovoz P.P.1, Koz’minykh V.O.2, Gorbunova A.V.3, Slepukhin P.A.4,5, El’tsov O.S.5, Ganebnykh I.N.4,5, Kuzmin A.V.6
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Affiliations:
- Orenburg Branch
- Perm State Humanitary Pedagogical University
- Orenburg State University
- I.Ya. Postovskii Institute of Organic Synthesis
- Ural Federal University named after the first President of Russia B.N. Yeltsin
- Institute of Solid State Physics of Russian Academy of Sciences
- Issue: Vol 86, No 11 (2016)
- Pages: 2427-2436
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/216481
- DOI: https://doi.org/10.1134/S1070363216110050
- ID: 216481
Cite item
Abstract
The two-step method of synthesis of 1,3,4,6-tetraoxocompounds with different terminal substituents is developed. By condensation of alkyl methyl ketones with dimethyl oxalate new 1,6-dialkyl-substituted 1,3,4,6-tetraoxohexanes are obtained. The esters of 3,4,6-trioxoalkanoic acids are synthesized by the condensation reaction of alkyl acetates with dialkyl oxalates and alkyl methyl ketones. By the reaction of ethyl acetate with diethyl oxalate and methyl acetate the mixed diester of 3,4-dioxo-1,6-hexanedioic (ketipic) acid has been first prepared. Specific structural features of the synthesized compounds are discussed basing on the data of the IR, NMR, and XRD diffraction (XRD) analysis.
About the authors
P. P. Mukovoz
Orenburg Branch
Author for correspondence.
Email: mpp27@mail.ru
Russian Federation, pr. Pobedy 75, Orenburg, 460018
V. O. Koz’minykh
Perm State Humanitary Pedagogical University
Email: mpp27@mail.ru
Russian Federation, Perm
A. V. Gorbunova
Orenburg State University
Email: mpp27@mail.ru
Russian Federation, Orenburg
P. A. Slepukhin
I.Ya. Postovskii Institute of Organic Synthesis; Ural Federal University named after the first President of Russia B.N. Yeltsin
Email: mpp27@mail.ru
Russian Federation, Yekaterinburg; Yekaterinburg
O. S. El’tsov
Ural Federal University named after the first President of Russia B.N. Yeltsin
Email: mpp27@mail.ru
Russian Federation, Yekaterinburg
I. N. Ganebnykh
I.Ya. Postovskii Institute of Organic Synthesis; Ural Federal University named after the first President of Russia B.N. Yeltsin
Email: mpp27@mail.ru
Russian Federation, Yekaterinburg; Yekaterinburg
A. V. Kuzmin
Institute of Solid State Physics of Russian Academy of Sciences
Email: mpp27@mail.ru
Russian Federation, Chernogolovka
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