Email this article Synthesis, reactions, and antimicrobial activity of some novel fused thiazolo[3,2-a]pyrimidine-5H-indeno[1,2-d]pyrimidine derivatives
- Authors: Khalifa N.M.1,2, Nossier E.S.3, Al-Omar M.A.1, Amr A.E.1,4
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Affiliations:
- Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy
- Department of Therapeutical Chemistry, Pharmaceutical and Drug Industries Division
- Department of Pharmaceutical Chemistry, Faculty of Pharmacy (Girls)
- Applied Chemistry Department National Research Center
- Issue: Vol 86, No 8 (2016)
- Pages: 1948-1953
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/216049
- DOI: https://doi.org/10.1134/S1070363216080284
- ID: 216049
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Abstract
Series of novel substituted thioxopyrimidine and thiazolo[3,2-a]pyrimidine compounds that combine various heteroaryl rings have been synthesized via Biginelli one-pot three-component reaction and elucidated with chemical and spectral analysis. Several products were tested for their antimicrobial properties.
About the authors
N. M. Khalifa
Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy; Department of Therapeutical Chemistry, Pharmaceutical and Drug Industries Division
Author for correspondence.
Email: nagykhalifa@hotmail.com
Saudi Arabia, Riyadh, 11451; Dokki, Cairo, 12622
E. S. Nossier
Department of Pharmaceutical Chemistry, Faculty of Pharmacy (Girls)
Email: nagykhalifa@hotmail.com
Egypt, Cairo
M. A. Al-Omar
Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy
Email: nagykhalifa@hotmail.com
Saudi Arabia, Riyadh, 11451
A. E. Amr
Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy; Applied Chemistry Department National Research Center
Email: nagykhalifa@hotmail.com
Saudi Arabia, Riyadh, 11451; Dokki, Cairo
