Mild regioselective iodination of pyrazoles using n-butyltriphenylphosphonium peroxodisulfate


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Abstract

A practical, efficient and inexpensive method of synthesis of iodopyrazoles by the reaction of pyrazoles with iodine using n-butyltriphenylphosphonium peroxodisulfate as an oxidant at room temperature is reported. The use of n-butyltriphenylphosphonium peroxodisulfate is feasible due to its easy preparation and handling, high stability and activity.

About the authors

M. Gorjizadeh

Department of Chemistry, Shooshtar Branch

Author for correspondence.
Email: m.gorjizadeh@iau-shoushtar.ac.ir
Iran, Islamic Republic of, Daneshgah Shooshtar

M. Afshari

Department of Chemistry, Shooshtar Branch

Email: m.gorjizadeh@iau-shoushtar.ac.ir
Iran, Islamic Republic of, Daneshgah Shooshtar

M. Naseh

Department of Chemistry, Dezful Branch

Email: m.gorjizadeh@iau-shoushtar.ac.ir
Iran, Islamic Republic of, Dezful


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