Ultrasound-assisted synthesis of pyrazolo[1,2-b]phthalazines and dihydrospiro[indoline-3,1'-pyrazolo[1,2-b]phthalazines] using TBAF as an efficient phase-transfer catalyst
- Authors: Kefayati H.1, Delafrooz A.1, Homayoon S.1
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Affiliations:
- Department of Chemistry, Rasht Branch
- Issue: Vol 86, No 7 (2016)
- Pages: 1735-1740
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/215810
- DOI: https://doi.org/10.1134/S107036321607032X
- ID: 215810
Cite item
Abstract
Tetrabutylammonim fluoride has been used as an efficient catalyst for synthesis of pyrazolo[1,2-b]-phthalazine-5,10-diones and dihydrospiro[indoline-3,1'-pyrazolo[1,2-b]phthalazines] by one-pot three-component reaction of phthalhydrazide, aromatic aldehydes or isatin derivatives, with malononitrile in water under ultrasond irradiation. This rapid method gave the products in high yield.
About the authors
H. Kefayati
Department of Chemistry, Rasht Branch
Author for correspondence.
Email: kefayati@iaurasht.ac.ir
Iran, Islamic Republic of, Rasht
A. Delafrooz
Department of Chemistry, Rasht Branch
Email: kefayati@iaurasht.ac.ir
Iran, Islamic Republic of, Rasht
S. Homayoon
Department of Chemistry, Rasht Branch
Email: kefayati@iaurasht.ac.ir
Iran, Islamic Republic of, Rasht