Synthesis and reactions of novel pyridine-bridged-2,6-bis-carboxamide hydrazones


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Abstract

A number of new hydrazones bearing pyridine-2,6-bis-carboxamides were synthesized and elucidated by spectral and elemental analysis. 2,6-Bis-carboxamide pyridine hydrazide was treated with various active carbonyl compounds containing formyl or methanoyl groups to give hydrazones and Schiff bases.

About the authors

N. M. Khalifa

Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy; Department of Therapeutical Chemistry, Pharmaceutical and Drug Industries Division

Author for correspondence.
Email: nagykhalifa@hotmail.com
Saudi Arabia, Riyadh, 11451; Dokki, Cairo, 12622

N. M. Sabry

Chemistry Department, Girls College of Science; Applied Organic Chemistry Department

Email: nagykhalifa@hotmail.com
Saudi Arabia, Abha, 9004; Dokki, Cairo, 12622

A. E. Amr

Pharmaceutical Chemistry Department, Drug Exploration & Development Chair (DEDC), College of Pharmacy; Applied Organic Chemistry Department

Email: nagykhalifa@hotmail.com
Saudi Arabia, Riyadh, 11451; Dokki, Cairo, 12622


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