Synthesis of novel 1-benzyl/aryl-4-{[(1-aryl-1 H -1,2,3-triazol-4-yl)methoxy]methyl}-1 H -1,2,3-triazole derivatives and evaluation of their antimicrobial activity

B. J. Reddy; V. P. Reddy; G. L. Goud; Y. J. Rao; Premkumar; K. Supriya

doi:10.1134/S107036321606030X

Synthesis of novel 1-benzyl/aryl-4-{[(1-aryl-1H-1,2,3-triazol-4-yl)methoxy]methyl}-1H-1,2,3-triazole derivatives and evaluation of their antimicrobial activity

Authors: Reddy B.J.¹, Reddy V.P.¹, Goud G.L.¹, Rao Y.J.¹, Premkumar ², Supriya K.³
Affiliations:
1. Department of Chemistry
2. Department of Genetics
3. Department of Chemistry, University College of Science
Issue: Vol 86, No 6 (2016)
Pages: 1424-1429
Section: Article
URL: https://journals.rcsi.science/1070-3632/article/view/215450
DOI: https://doi.org/10.1134/S107036321606030X
ID: 215450

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Abstract

A series of 1-benzyl/aryl-4-{[(1-aryl-1H-1,2,3-triazol-4-yl)methoxy]methyl}-1H-1,2,3-triazole derivatives were synthesized via Cu(I) catalyzed reaction between terminal alkyne and substituted aryl or benzyl azides. The synthesized triazoles were characterized by 1H NMR, 13C NMR, IR, and mass spectral techniques. All the synthesized compounds were screened for their antimicrobial activity.