Microwave assisted selective synthesis of (E)-1-(4-Chloro-7-hydroxy-2-aryl-2H-chromen-6-yl)-3-arylprop-2-en-1-ones and their antimicrobial activity
- Authors: Ashok D.1, Sarasija M.1, Shravani D.1, Vijayalaxmi B.1, Sudershan K.1
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Affiliations:
- Green and Medicinal Chemistry Laboratory, Department of Chemistry
- Issue: Vol 86, No 4 (2016)
- Pages: 930-933
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/214757
- DOI: https://doi.org/10.1134/S1070363216040290
- ID: 214757
Cite item
Abstract
A series of new (E)-1-(4-chloro-7-hydroxy-2-aryl-2H-chromen-6-yl)-3-arylprop-2-en-1-ones (2a–2f) have been synthesized by selective mono cyclization of 4,6-dicinnamoyl resorcinols (1a–1f) using Vilsmeier–Haack reagent under conventional heating and microwave irradiation. The structures of the synthesized compounds have been elucidated by elemental analysis, IR, 1H NMR, 13C NMR and Mass spectral data. The synthesized compounds were tested in vitro for antimicrobial activity.
About the authors
D. Ashok
Green and Medicinal Chemistry Laboratory, Department of Chemistry
Author for correspondence.
Email: ashokdou@gmail.com
India, Hyderabad, 500007
M. Sarasija
Green and Medicinal Chemistry Laboratory, Department of Chemistry
Email: ashokdou@gmail.com
India, Hyderabad, 500007
D. Shravani
Green and Medicinal Chemistry Laboratory, Department of Chemistry
Email: ashokdou@gmail.com
India, Hyderabad, 500007
B. Vijayalaxmi
Green and Medicinal Chemistry Laboratory, Department of Chemistry
Email: ashokdou@gmail.com
India, Hyderabad, 500007
K. Sudershan
Green and Medicinal Chemistry Laboratory, Department of Chemistry
Email: ashokdou@gmail.com
India, Hyderabad, 500007
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