Email this article Synthesis and hypoglycemic activity of methyl-6-aryl(hetaryl)-5-(2-furanoyl)-3,6-dihydrotetrazolo[1,5-a]pyrimidine-4-carboxylates
- Authors: Gein V.L.1, Zamaraeva T.M.1, Mishunin V.V.1, Kotegov V.P.2
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Affiliations:
- Perm State Pharmaceutical Academy
- Perm State National Research University
- Issue: Vol 86, No 2 (2016)
- Pages: 286-290
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/213713
- DOI: https://doi.org/10.1134/S1070363216020134
- ID: 213713
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Abstract
Three-component reaction of methyl 2-furanoylpyruvate with an aromatic aldehyde and 5-aminotetrazole monohydrate has afforded methyl 6-aryl(hetaryl)-5-(2-furanoyl)-3,6-dihydrotetrazolo[1,5-a]-pyrimidine-4-carboxylates. Hypoglycemic activity of the prepared compounds has been studied.
About the authors
V. L. Gein
Perm State Pharmaceutical Academy
Author for correspondence.
Email: geinvl48@mail.ru
Russian Federation, ul. Polevaya 2, Perm, 614990
T. M. Zamaraeva
Perm State Pharmaceutical Academy
Email: geinvl48@mail.ru
Russian Federation, ul. Polevaya 2, Perm, 614990
V. V. Mishunin
Perm State Pharmaceutical Academy
Email: geinvl48@mail.ru
Russian Federation, ul. Polevaya 2, Perm, 614990
V. P. Kotegov
Perm State National Research University
Email: geinvl48@mail.ru
Russian Federation, Perm
