SnCl4: An efficient and inexpensive promoter for synthesis of ω-functionalized alkyl 1,2-trans-glycosides from 1-O-pivaloyl donor
- Authors: Nikseresht A.1
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Affiliations:
- Department of Chemistry
- Issue: Vol 86, No 1 (2016)
- Pages: 167-172
- Section: Article
- URL: https://journals.rcsi.science/1070-3632/article/view/213554
- DOI: https://doi.org/10.1134/S1070363216010266
- ID: 213554
Cite item
Abstract
SnCl4-promoted reactions of perpivaloylated lactose with various alcohols were studied in the presence or absence of an additive, CaCO3. SnCl4 was found to promote the 1,2-trans-glycosylation of alcohols in CH2Cl2 at 0°C in a stereo controlled manner with β-selectivity. The corresponding glycosides were isolated in high yields.
About the authors
A. Nikseresht
Department of Chemistry
Author for correspondence.
Email: a_nik55@yahoo.com
Iran, Islamic Republic of, Tehran, 19395-4697