Мақаланы E-mail арқылы жіберу A novel dinuclear Pd(II) complex dibridged by 2,2-iminodibenzoic acid: Synthesis, characterization, and biological activity
- Авторлар: Gao E.J.1, Ma X.Y.1, Wang B.1, Meng Y.1, Zhao F.C.1, Jin H.T.1, Liu S.J.1, Ge J.1, Sun Y.G.1, Zhang W.Z.1, Zhu M.C.1
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Мекемелер:
- Key Laboratory of the Inorganic Molecule-Based Chemistry of Liaoning Province and Laboratory of Coordination Chemistry
- Шығарылым: Том 42, № 11 (2016)
- Беттер: 749-754
- Бөлім: Article
- URL: https://journals.rcsi.science/1070-3284/article/view/213348
- DOI: https://doi.org/10.1134/S1070328416110038
- ID: 213348
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Аннотация
The novel dinuclear complex [Pd2(L)2(Phen)2] (Phen = 1,10-phenanthroline, H2L = 2,2'-iminodibenzoic acid) was synthesized and characterized by IR spectra, element analysis, and X-ray single-crystal diffraction (СIF file CCDC no. 1469344). The competitive binding study with ethidium bromide (EtBr) was tested by fluorescence measurement. The result indicated that the complex has an ability to displace the EtBr bound to DNA. Gel electrophoresis assay demonstrated the ability of the complex to cleave the HL-60 DNA. Apoptotic research indicated that [Pd2(L)2(Phen)2] exhibited significant cancer cell inhibitory rate.
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Авторлар туралы
E. Gao
Key Laboratory of the Inorganic Molecule-Based Chemistry of Liaoning Province and Laboratory of Coordination Chemistry
Хат алмасуға жауапты Автор.
Email: enjungao@163.com
ҚХР, Shenyang, 110142
X. Ma
Key Laboratory of the Inorganic Molecule-Based Chemistry of Liaoning Province and Laboratory of Coordination Chemistry
Email: mczhu@syuct.edu.cn
ҚХР, Shenyang, 110142
B. Wang
Key Laboratory of the Inorganic Molecule-Based Chemistry of Liaoning Province and Laboratory of Coordination Chemistry
Email: mczhu@syuct.edu.cn
ҚХР, Shenyang, 110142
Y. Meng
Key Laboratory of the Inorganic Molecule-Based Chemistry of Liaoning Province and Laboratory of Coordination Chemistry
Email: mczhu@syuct.edu.cn
ҚХР, Shenyang, 110142
F. Zhao
Key Laboratory of the Inorganic Molecule-Based Chemistry of Liaoning Province and Laboratory of Coordination Chemistry
Email: mczhu@syuct.edu.cn
ҚХР, Shenyang, 110142
H. Jin
Key Laboratory of the Inorganic Molecule-Based Chemistry of Liaoning Province and Laboratory of Coordination Chemistry
Email: mczhu@syuct.edu.cn
ҚХР, Shenyang, 110142
S. Liu
Key Laboratory of the Inorganic Molecule-Based Chemistry of Liaoning Province and Laboratory of Coordination Chemistry
Email: mczhu@syuct.edu.cn
ҚХР, Shenyang, 110142
J. Ge
Key Laboratory of the Inorganic Molecule-Based Chemistry of Liaoning Province and Laboratory of Coordination Chemistry
Email: mczhu@syuct.edu.cn
ҚХР, Shenyang, 110142
Y. Sun
Key Laboratory of the Inorganic Molecule-Based Chemistry of Liaoning Province and Laboratory of Coordination Chemistry
Email: mczhu@syuct.edu.cn
ҚХР, Shenyang, 110142
W. Zhang
Key Laboratory of the Inorganic Molecule-Based Chemistry of Liaoning Province and Laboratory of Coordination Chemistry
Email: mczhu@syuct.edu.cn
ҚХР, Shenyang, 110142
M. Zhu
Key Laboratory of the Inorganic Molecule-Based Chemistry of Liaoning Province and Laboratory of Coordination Chemistry
Хат алмасуға жауапты Автор.
Email: mczhu@syuct.edu.cn
ҚХР, Shenyang, 110142
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