Отправить статью по E-mail A novel dinuclear Pd(II) complex dibridged by 2,2-iminodibenzoic acid: Synthesis, characterization, and biological activity
- Авторы: Gao E.J.1, Ma X.Y.1, Wang B.1, Meng Y.1, Zhao F.C.1, Jin H.T.1, Liu S.J.1, Ge J.1, Sun Y.G.1, Zhang W.Z.1, Zhu M.C.1
-
Учреждения:
- Key Laboratory of the Inorganic Molecule-Based Chemistry of Liaoning Province and Laboratory of Coordination Chemistry
- Выпуск: Том 42, № 11 (2016)
- Страницы: 749-754
- Раздел: Article
- URL: https://journals.rcsi.science/1070-3284/article/view/213348
- DOI: https://doi.org/10.1134/S1070328416110038
- ID: 213348
Цитировать
Открытый доступ
Доступ предоставлен
Только для подписчиков
Аннотация
The novel dinuclear complex [Pd2(L)2(Phen)2] (Phen = 1,10-phenanthroline, H2L = 2,2'-iminodibenzoic acid) was synthesized and characterized by IR spectra, element analysis, and X-ray single-crystal diffraction (СIF file CCDC no. 1469344). The competitive binding study with ethidium bromide (EtBr) was tested by fluorescence measurement. The result indicated that the complex has an ability to displace the EtBr bound to DNA. Gel electrophoresis assay demonstrated the ability of the complex to cleave the HL-60 DNA. Apoptotic research indicated that [Pd2(L)2(Phen)2] exhibited significant cancer cell inhibitory rate.
Ключевые слова
Об авторах
E. Gao
Key Laboratory of the Inorganic Molecule-Based Chemistry of Liaoning Province and Laboratory of Coordination Chemistry
Автор, ответственный за переписку.
Email: enjungao@163.com
Китай, Shenyang, 110142
X. Ma
Key Laboratory of the Inorganic Molecule-Based Chemistry of Liaoning Province and Laboratory of Coordination Chemistry
Email: mczhu@syuct.edu.cn
Китай, Shenyang, 110142
B. Wang
Key Laboratory of the Inorganic Molecule-Based Chemistry of Liaoning Province and Laboratory of Coordination Chemistry
Email: mczhu@syuct.edu.cn
Китай, Shenyang, 110142
Y. Meng
Key Laboratory of the Inorganic Molecule-Based Chemistry of Liaoning Province and Laboratory of Coordination Chemistry
Email: mczhu@syuct.edu.cn
Китай, Shenyang, 110142
F. Zhao
Key Laboratory of the Inorganic Molecule-Based Chemistry of Liaoning Province and Laboratory of Coordination Chemistry
Email: mczhu@syuct.edu.cn
Китай, Shenyang, 110142
H. Jin
Key Laboratory of the Inorganic Molecule-Based Chemistry of Liaoning Province and Laboratory of Coordination Chemistry
Email: mczhu@syuct.edu.cn
Китай, Shenyang, 110142
S. Liu
Key Laboratory of the Inorganic Molecule-Based Chemistry of Liaoning Province and Laboratory of Coordination Chemistry
Email: mczhu@syuct.edu.cn
Китай, Shenyang, 110142
J. Ge
Key Laboratory of the Inorganic Molecule-Based Chemistry of Liaoning Province and Laboratory of Coordination Chemistry
Email: mczhu@syuct.edu.cn
Китай, Shenyang, 110142
Y. Sun
Key Laboratory of the Inorganic Molecule-Based Chemistry of Liaoning Province and Laboratory of Coordination Chemistry
Email: mczhu@syuct.edu.cn
Китай, Shenyang, 110142
W. Zhang
Key Laboratory of the Inorganic Molecule-Based Chemistry of Liaoning Province and Laboratory of Coordination Chemistry
Email: mczhu@syuct.edu.cn
Китай, Shenyang, 110142
M. Zhu
Key Laboratory of the Inorganic Molecule-Based Chemistry of Liaoning Province and Laboratory of Coordination Chemistry
Автор, ответственный за переписку.
Email: mczhu@syuct.edu.cn
Китай, Shenyang, 110142
Дополнительные файлы
