Glycogen phosphorylase inhibitors in the regulation of carbohydrate metabolism in type 2 diabetes
- Authors: Spasov A.A.1, Chepljaeva N.I.1, Vorob’ev E.S.1
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Affiliations:
- Volgograd State Medical University
- Issue: Vol 42, No 2 (2016)
- Pages: 133-142
- Section: Article
- URL: https://journals.rcsi.science/1068-1620/article/view/227858
- DOI: https://doi.org/10.1134/S1068162016020138
- ID: 227858
Cite item
Abstract
Glycogen phosphorylase as a potential target for design of new drugs for the treatment of diabetes mellitus type 2, its main role and functions, as well as the ligands that bind to different sites of the enzyme are discussed in this review.
About the authors
A. A. Spasov
Volgograd State Medical University
Email: natalja-chepljaeva@rambler.ru
Russian Federation, Volgograd, pl. Pavshikh Bortsov 1, Volgograd, 1400131
N. I. Chepljaeva
Volgograd State Medical University
Author for correspondence.
Email: natalja-chepljaeva@rambler.ru
Russian Federation, Volgograd, pl. Pavshikh Bortsov 1, Volgograd, 1400131
E. S. Vorob’ev
Volgograd State Medical University
Email: natalja-chepljaeva@rambler.ru
Russian Federation, Volgograd, pl. Pavshikh Bortsov 1, Volgograd, 1400131