Glycogen phosphorylase inhibitors in the regulation of carbohydrate metabolism in type 2 diabetes


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Abstract

Glycogen phosphorylase as a potential target for design of new drugs for the treatment of diabetes mellitus type 2, its main role and functions, as well as the ligands that bind to different sites of the enzyme are discussed in this review.

About the authors

A. A. Spasov

Volgograd State Medical University

Email: natalja-chepljaeva@rambler.ru
Russian Federation, Volgograd, pl. Pavshikh Bortsov 1, Volgograd, 1400131

N. I. Chepljaeva

Volgograd State Medical University

Author for correspondence.
Email: natalja-chepljaeva@rambler.ru
Russian Federation, Volgograd, pl. Pavshikh Bortsov 1, Volgograd, 1400131

E. S. Vorob’ev

Volgograd State Medical University

Email: natalja-chepljaeva@rambler.ru
Russian Federation, Volgograd, pl. Pavshikh Bortsov 1, Volgograd, 1400131


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