Email this article A New Approach for the Hybridization Analysis of Pathogens
- Authors: Kostina E.V.1, Sinyakov A.N.1, Ryabinin V.A.1
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Affiliations:
- Novosibirsk Institute of Chemical Biology and Fundamental Medicine, Siberian Branch, Russian Academy of Sciences
- Issue: Vol 45, No 6 (2019)
- Pages: 842-844
- Section: Letter to Editor
- URL: https://journals.rcsi.science/1068-1620/article/view/229369
- DOI: https://doi.org/10.1134/S1068162019060244
- ID: 229369
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Abstract
The paper proposes a new variant for registering pathogens in the many-probes one-spot hybridization system. Using the example of Chlamydia trachomatis detection in blood serum samples, it has been demonstrated that hybridization of the analyzed DNA is characterized by a considerably stronger signal and higher specificity which may be advantageous for PointOfCare diagnostics (POC diagnostics).
About the authors
E. V. Kostina
Novosibirsk Institute of Chemical Biology and Fundamental Medicine, Siberian Branch, Russian Academy of Sciences
Author for correspondence.
Email: kostinaelena@mail.ru
Russian Federation, Novosibirsk, 630090
A. N. Sinyakov
Novosibirsk Institute of Chemical Biology and Fundamental Medicine, Siberian Branch, Russian Academy of Sciences
Email: kostinaelena@mail.ru
Russian Federation, Novosibirsk, 630090
V. A. Ryabinin
Novosibirsk Institute of Chemical Biology and Fundamental Medicine, Siberian Branch, Russian Academy of Sciences
Email: kostinaelena@mail.ru
Russian Federation, Novosibirsk, 630090
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