Antistress properties of sodium 1-N-acetylamino-1-carboxy-2-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate
- 作者: Zhigacheva I.1, Rasulov M.2
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隶属关系:
- M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences
- State Research Institute for Chemistry and Technology of Organoelement Compounds
- 期: 卷 67, 编号 4 (2018)
- 页面: 721-725
- 栏目: Full Article
- URL: https://journals.rcsi.science/1066-5285/article/view/242447
- DOI: https://doi.org/10.1007/s11172-018-2128-1
- ID: 242447
如何引用文章
详细
The effect of a spatially-hindered phenol, namely sodium 1-N-acetylamino-1-carboxy-2-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate, on the functionality of mitochondria of rat liver was studied. Stress impact caused a 3 to 4-fold increase in the fluorescence intensity of the products of lipid peroxidation (LPO) in the membranes of these organelles. The preparation reduced the intensity of LPO to the control level, which was conductive to maintaining high functional activity of the mitochondria. Prevention of mitochondrial dysfunction was probably associated with an increase in the resistance of animals to stress factors.
作者简介
I. Zhigacheva
M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences
编辑信件的主要联系方式.
Email: zhigacheva@mail.ru
俄罗斯联邦, 4 ul. Kosygina, Moscow, Russian Federation, 119334
M. Rasulov
State Research Institute for Chemistry and Technology of Organoelement Compounds
Email: zhigacheva@mail.ru
俄罗斯联邦, 38 sh. Entuziastov, Moscow, Russian Federation, 105118