Synthetic approaches to conjugation of aminoadamantanes and carbazoles

V. B. Sokolov; A. Yu. Aksinenko; T. A. Epishina; T. V. Goreva; S. O. Bachurin

doi:10.1007/s11172-017-1988-0

Synthetic approaches to conjugation of aminoadamantanes and carbazoles

作者: Sokolov V.¹, Aksinenko A.¹, Epishina T.¹, Goreva T.¹, Bachurin S.¹
隶属关系:
1. Institute of Physiologically Active Substances, Russian Academy of Sciences
期: 卷 66, 编号 11 (2017)
页面: 2110-2114
栏目: Full Article
URL: https://journals.rcsi.science/1066-5285/article/view/241581
DOI: https://doi.org/10.1007/s11172-017-1988-0
ID: 241581

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Five different synthetic approaches for the conjugation of carbazoles with aminoadamantanes via propylene, 2-hydroxypropylene, 1-oxopropylene, 1-oxoethylene and triazole spacers have been proposed. The corresponding mesylate-, acrylate-, chloroacetate-, propargyl-, azido- and epoxy-containing carbazoles and aminoadamantanes were used as the starting compounds.