Complexation of calix[4]resorcinol with phosphorylacetic acid hydrazides possessing neurotrophic activity


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The structures of the molecular complexes based on calix[4]resorcinol bearing a p-tolyl moiety at the lower rim with phosenazid (2-(diphenylphosphoryl)acetohydrazide) and CAPAH (2-{[4-(dimethylamino)phenyl](2-chloroethoxy)phosphoryl}acetohydrazide) were studied by NMR, IR, and UV spectroscopy and X-ray powder diffraction. The results of the screening of neurotrophic activities of the molecular complexes are presented.

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E. Gavrilova

Kazan National Research Technological University

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Email: gavrilova_elena_@mail.ru
俄罗斯联邦, 68 ul. K. Marksa, Kazan, 420015

M. Sajfutdinova

Kazan National Research Technological University

Email: gavrilova_elena_@mail.ru
俄罗斯联邦, 68 ul. K. Marksa, Kazan, 420015

R. Tarasova

Kazan National Research Technological University

Email: gavrilova_elena_@mail.ru
俄罗斯联邦, 68 ul. K. Marksa, Kazan, 420015

N. Shatalova

Kazan National Research Technological University

Email: gavrilova_elena_@mail.ru
俄罗斯联邦, 68 ul. K. Marksa, Kazan, 420015

I. Semina

Kazan State Medical University

Email: gavrilova_elena_@mail.ru
俄罗斯联邦, 49 ul. Butlerova, Kazan, 420012

A. Gubajdullin

A. E. Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center of the Russian Academy of Sciences

Email: gavrilova_elena_@mail.ru
俄罗斯联邦, 8 ul. Akad. Arbuzova, Kazan, 420088


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