Отправить статью по E-mail Synthesis and biological activity of 3-guanidino-6-R-imidazo[1,2-b]- and 6-guanidino-3-R-[1,2,4]triazolo[4,3-b][1,2,4,5]tetrazines
- Авторы: Ishmetova R.1, Ignatenko N.1, Korotina A.1, Ganebnykh I.1, Slepukhin P.1,2, Babkova V.3, Gerasimova N.4, Evstigneeva N.4, Zilberberg N.4, Kungurov N.4, Rusinov G.1,2, Spasov A.3, Chupakhin O.1,2
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Учреждения:
- I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
- Ural Federal University named after the first President of Russia B. N. Yeltsin
- Volgograd State Medical University, Ministry of Health of the Russian Federation
- Ural Research Institute of Dermatovenereology and Immunopathology
- Выпуск: Том 67, № 11 (2018)
- Страницы: 2079-2087
- Раздел: Full Articles
- URL: https://journals.rcsi.science/1066-5285/article/view/243186
- DOI: https://doi.org/10.1007/s11172-018-2332-z
- ID: 243186
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Аннотация
The reaction of azoloannulated [1,2,4,5]tetrazines with guanidine was studied. New 3-guanidinoimidazo[1,2-b]- and 6-guanidino[1,2,4]triazolo[4,3-b] [1,2,4,5]tetrazines were synthesized using the nucleophilic substitution methodology. Compounds with high antibacterial and antiglycation activity were revealed.
Об авторах
R. Ishmetova
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
Автор, ответственный за переписку.
Email: iri@ios.uran.ru
Россия, 22/20 ul. S. Kovalevskoi, Yekaterinburg, 620137
N. Ignatenko
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
Email: iri@ios.uran.ru
Россия, 22/20 ul. S. Kovalevskoi, Yekaterinburg, 620137
A. Korotina
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
Email: iri@ios.uran.ru
Россия, 22/20 ul. S. Kovalevskoi, Yekaterinburg, 620137
I. Ganebnykh
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
Email: iri@ios.uran.ru
Россия, 22/20 ul. S. Kovalevskoi, Yekaterinburg, 620137
P. Slepukhin
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences; Ural Federal University named after the first President of Russia B. N. Yeltsin
Email: iri@ios.uran.ru
Россия, 22/20 ul. S. Kovalevskoi, Yekaterinburg, 620137; 19 ul. Mira, Yekaterinburg, 620002
V. Babkova
Volgograd State Medical University, Ministry of Health of the Russian Federation
Email: iri@ios.uran.ru
Россия, 1 pl. Pavshikh Bortsov, Volgograd, 400131
N. Gerasimova
Ural Research Institute of Dermatovenereology and Immunopathology
Email: iri@ios.uran.ru
Россия, 8 ul. Shcherbakova, Yekaterinburg, 620076
N. Evstigneeva
Ural Research Institute of Dermatovenereology and Immunopathology
Email: iri@ios.uran.ru
Россия, 8 ul. Shcherbakova, Yekaterinburg, 620076
N. Zilberberg
Ural Research Institute of Dermatovenereology and Immunopathology
Email: iri@ios.uran.ru
Россия, 8 ul. Shcherbakova, Yekaterinburg, 620076
N. Kungurov
Ural Research Institute of Dermatovenereology and Immunopathology
Email: iri@ios.uran.ru
Россия, 8 ul. Shcherbakova, Yekaterinburg, 620076
G. Rusinov
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences; Ural Federal University named after the first President of Russia B. N. Yeltsin
Email: iri@ios.uran.ru
Россия, 22/20 ul. S. Kovalevskoi, Yekaterinburg, 620137; 19 ul. Mira, Yekaterinburg, 620002
A. Spasov
Volgograd State Medical University, Ministry of Health of the Russian Federation
Email: iri@ios.uran.ru
Россия, 1 pl. Pavshikh Bortsov, Volgograd, 400131
O. Chupakhin
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences; Ural Federal University named after the first President of Russia B. N. Yeltsin
Email: iri@ios.uran.ru
Россия, 22/20 ul. S. Kovalevskoi, Yekaterinburg, 620137; 19 ul. Mira, Yekaterinburg, 620002
