Comparative reactivity of hydroxyketones and their derivatives in the reactions with N,S-nucleophiles


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Resumo

The reactions of thiosemicarbazide (TSC), thiocarbohydrazide, and hydrazine thiocarbamate with oxyketones, haloketones, and derivatives of acetylenic alcohols were studied. Thiadiazines bearing exocyclic thio and hydrazo groups were synthesized. Acetylenic alcohols react with TSC to give the corresponding thiazolidines. The reactions of halo derivatives of acetylenic alcohols with TSC are complicated by side reactions.

Sobre autores

E. Pulatov

V. I. Nikitin Institute of Chemistry, Academy of Sciences of the Republic of Tajikistan

Email: coordin@yandex.ru
Tajiquistão, 299/2 ul. Aini, 734063, Dushanbe

M. Isobaev

V. I. Nikitin Institute of Chemistry, Academy of Sciences of the Republic of Tajikistan

Autor responsável pela correspondência
Email: coordin@yandex.ru
Tajiquistão, 299/2 ul. Aini, 734063, Dushanbe

B. Mavlonov

V. I. Nikitin Institute of Chemistry, Academy of Sciences of the Republic of Tajikistan

Email: coordin@yandex.ru
Tajiquistão, 299/2 ul. Aini, 734063, Dushanbe

T. Abdullaev

V. I. Nikitin Institute of Chemistry, Academy of Sciences of the Republic of Tajikistan

Email: coordin@yandex.ru
Tajiquistão, 299/2 ul. Aini, 734063, Dushanbe


Declaração de direitos autorais © Springer Science+Business Media, LLC, part of Springer Nature, 2018

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