Enviar artigo por via de e-mail Synthesis of sodium 5-sulfate-ivermectin and disodium 4″,5-disulfate-ivermectin
- Autores: Shchetinina M.A.1, Chernoburova E.I.1, Kolotyrkina N.G.1, Dzhafarov M.K.2, Vasilevich F.I.2, Zavarzin I.V.1
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Afiliações:
- N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
- K. I. Skryabin Moscow State Academy of Veterinary Medicine and Biotechnology
- Edição: Volume 67, Nº 5 (2018)
- Páginas: 836-839
- Seção: Full Articles
- URL: https://journals.rcsi.science/1066-5285/article/view/242512
- DOI: https://doi.org/10.1007/s11172-018-2146-z
- ID: 242512
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Resumo
Treatment of ivermectin with sulfuric acid–acetic anhydride in pyridine gives sodium 5-sulfate-ivermectin and disodium 4″,5-disulfate-ivermectin. The synthesized salts are water-soluble compounds with promising antiparasitic activity.
Sobre autores
M. Shchetinina
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
Email: zavi@ioc.ac.ru
Rússia, 47 Leninsky prosp., Moscow, 119991
E. Chernoburova
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
Email: zavi@ioc.ac.ru
Rússia, 47 Leninsky prosp., Moscow, 119991
N. Kolotyrkina
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
Email: zavi@ioc.ac.ru
Rússia, 47 Leninsky prosp., Moscow, 119991
M. Dzhafarov
K. I. Skryabin Moscow State Academy of Veterinary Medicine and Biotechnology
Email: zavi@ioc.ac.ru
Rússia, 23 ul. Akad. Skryabina, Moscow, 109472
F. Vasilevich
K. I. Skryabin Moscow State Academy of Veterinary Medicine and Biotechnology
Email: zavi@ioc.ac.ru
Rússia, 23 ul. Akad. Skryabina, Moscow, 109472
I. Zavarzin
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
Autor responsável pela correspondência
Email: zavi@ioc.ac.ru
Rússia, 47 Leninsky prosp., Moscow, 119991
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