Molecular and crystal structure of 19-nor-4α(6-hydrazonocarbonyl-3,4,5-trihydroxytetrahydropyran-2-oxycarbonyl)-16-hydrazono-ent-beyeran

Resumo

X-ray crystallography was used to study molecular and crystal structure of 19-nor-4α-(6-hydrazonocarbonyl-3,4,5-trihydroxytetrahydropyran-2-oxycarbonyl)-16-hydrazono-ent-beyeran (1). The bulky hydrophilic substituents are on one side of the hydrophobic beyeran fragment, that leads to the layer-type crystal packing: the hydrophilic layers, in which molecules 1 and hydrate water molecules bound by the classic hydrogen bonds of the O—H...O—and N—H...O type alternate with hydrophobic layers formed by the ent-beyeran fragments.