电邮这篇文章 Antiproliferative activity of ruthenium and osmium clusters with phosphine ligands
- 作者: Nazarov A.A.1, Nosova Y.N.1, Mikhalev O.V.1, Kovaleva O.N.2, Dyson P.J.3, Milaeva E.R.1
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隶属关系:
- Department of Chemistry, M. V. Lomonosov Moscow State University
- I. M. Sechenov First Moscow State Medical University
- Swiss Federal Institute of Technology in Lausanne
- 期: 卷 65, 编号 2 (2016)
- 页面: 546-549
- 栏目: Full Articles
- URL: https://journals.rcsi.science/1066-5285/article/view/237279
- DOI: https://doi.org/10.1007/s11172-016-1335-x
- ID: 237279
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详细
New ruthenium and osmium carbonyl clusters with 1,3,5-triaza-7-phosphatricyclo-[3.3.1.13.7]decane and 3,7-diacetyl-1,3,7-triaza-5-phosphabicyclo[3.3.1]nonane ligands were synthesized using Me3NO as an initiator. The data on antiproliferative activity of new compounds against ovarian carcinoma cell cultures A2780 (cisplatin-sensitive) and A2780cisR (cisplatin-resistant) are reported. The dependence of cytotoxicity on the number of phosphine ligands was demonstrated.
作者简介
A. Nazarov
Department of Chemistry, M. V. Lomonosov Moscow State University
编辑信件的主要联系方式.
Email: nazarov@med.chem.msu.ru
俄罗斯联邦, Build. 3, 1 Leninskie Gory, Moscow, 119991
Yu. Nosova
Department of Chemistry, M. V. Lomonosov Moscow State University
Email: nazarov@med.chem.msu.ru
俄罗斯联邦, Build. 3, 1 Leninskie Gory, Moscow, 119991
O. Mikhalev
Department of Chemistry, M. V. Lomonosov Moscow State University
Email: nazarov@med.chem.msu.ru
俄罗斯联邦, Build. 3, 1 Leninskie Gory, Moscow, 119991
O. Kovaleva
I. M. Sechenov First Moscow State Medical University
Email: nazarov@med.chem.msu.ru
俄罗斯联邦, Build. 2, 8 ul. Trubetskaya, Moscow, 119991
P. Dyson
Swiss Federal Institute of Technology in Lausanne
Email: nazarov@med.chem.msu.ru
瑞士, Lausanne
E. Milaeva
Department of Chemistry, M. V. Lomonosov Moscow State University
Email: nazarov@med.chem.msu.ru
俄罗斯联邦, Build. 3, 1 Leninskie Gory, Moscow, 119991
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