电邮这篇文章 Nitro derivatives of 2,1,3-benzothiadiazole 1-oxides: synthesis, structural study, and NO release
- 作者: Konstantinova L.S.1, Knyazeva E.A.1, Gatilov Y.V.2, Zlotin S.G.1, Rakitin O.A.1
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隶属关系:
- N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
- N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences
- 期: 卷 67, 编号 1 (2018)
- 页面: 95-101
- 栏目: Article
- URL: https://journals.rcsi.science/1066-5285/article/view/241933
- DOI: https://doi.org/10.1007/s11172-018-2042-6
- ID: 241933
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详细
A convenient one-pot synthesis of nitro derivatives of 2,1,3-benzothiadiazole 1-oxides by the reaction of o-nitroanilines with sulfur monochloride was developed. The structural features of 4-nitrobenzothiadiazole and its N-oxide were considered. High in vitro release of nitric oxide (69%) was found for a 6-nitro-2,1,3-benzothiadiazole sample by the Griess assay, which indicated good prospects for this class of compounds.
作者简介
L. Konstantinova
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
Email: orakitin@ioc.ac.ru
俄罗斯联邦, 47 Leninsky prosp., Moscow, 119991
E. Knyazeva
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
Email: orakitin@ioc.ac.ru
俄罗斯联邦, 47 Leninsky prosp., Moscow, 119991
Yu. Gatilov
N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences
Email: orakitin@ioc.ac.ru
俄罗斯联邦, 9 prosp. Akad. Lavrent’eva, Novosibirsk, 630090
S. Zlotin
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
Email: orakitin@ioc.ac.ru
俄罗斯联邦, 47 Leninsky prosp., Moscow, 119991
O. Rakitin
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
编辑信件的主要联系方式.
Email: orakitin@ioc.ac.ru
俄罗斯联邦, 47 Leninsky prosp., Moscow, 119991
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