Probing Mechanical Characteristics of Living Fibroblasts via Atomic Force Microscopy
- 作者: Timoshchuk K.1, Khalisov M.1, Penniyaynen V.1, Krylov B.1, Ankudinov A.2
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隶属关系:
- Pavlov Institute of Physiology, Russian Academy of Sciences
- Ioffe Physical Technical Institute, Russian Academy of Sciences
- 期: 卷 45, 编号 9 (2019)
- 页面: 947-950
- 栏目: Article
- URL: https://journals.rcsi.science/1063-7850/article/view/208435
- DOI: https://doi.org/10.1134/S1063785019090293
- ID: 208435
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详细
Atomic force microscopy (AFM) measurements have revealed hardening of intact fibroblasts after treatment with colchicine. The reliability of AFM measurements was confirmed by the identification of cells the lateral response of which to indentation did not disturb the normal force contribution. AFM data on the mechanical characteristics of such cells admit an unambiguous interpretation.
作者简介
K. Timoshchuk
Pavlov Institute of Physiology, Russian Academy of Sciences
Email: alexander.ankudinov@mail.ioffe.ru
俄罗斯联邦, St. Petersburg, 199034
M. Khalisov
Pavlov Institute of Physiology, Russian Academy of Sciences
Email: alexander.ankudinov@mail.ioffe.ru
俄罗斯联邦, St. Petersburg, 199034
V. Penniyaynen
Pavlov Institute of Physiology, Russian Academy of Sciences
Email: alexander.ankudinov@mail.ioffe.ru
俄罗斯联邦, St. Petersburg, 199034
B. Krylov
Pavlov Institute of Physiology, Russian Academy of Sciences
Email: alexander.ankudinov@mail.ioffe.ru
俄罗斯联邦, St. Petersburg, 199034
A. Ankudinov
Ioffe Physical Technical Institute, Russian Academy of Sciences
编辑信件的主要联系方式.
Email: alexander.ankudinov@mail.ioffe.ru
俄罗斯联邦, St. Petersburg, 194021