An electrochemical aptasensor for cytochrome C, based on pillar[5]arene modified with Neutral Red
- 作者: Stepanova V.1, Shurpik D.1, Evtyugin V.2, Stoikov I.1, Evtyugin G.1, Gianik T.1,3
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隶属关系:
- Butlerov Institute of Chemistry
- Interdisciplinary Center for Analytical Microscopy
- Comenius University in Bratislava
- 期: 卷 72, 编号 4 (2017)
- 页面: 375-381
- 栏目: Articles
- URL: https://journals.rcsi.science/1061-9348/article/view/182373
- DOI: https://doi.org/10.1134/S1061934817040141
- ID: 182373
如何引用文章
详细
An electrochemical aptasensor is developed for the highly sensitive determination of cytochrome C, using a change in the redox current of Neutral Red covalently bound to terminal carboxyl groups of decasubstituted pillar[5]arene as a signal. The inclusion of the analyte into the complex with an aptamer reduces peaks of redox current of the dye through the dissociation of electron transfer chain in the surface layer. The aptasensor enables the determination of 1 nM to 1.0 mM of cytochrome C in the presence of 1000-fold excesses of albumin, polyethylene glycol, and lysozyme as models of interfering components in biological fluids.
作者简介
V. Stepanova
Butlerov Institute of Chemistry
Email: Gennady.Evtugyn@kpfu.ru
俄罗斯联邦, Kazan, 420008
D. Shurpik
Butlerov Institute of Chemistry
Email: Gennady.Evtugyn@kpfu.ru
俄罗斯联邦, Kazan, 420008
V. Evtyugin
Interdisciplinary Center for Analytical Microscopy
Email: Gennady.Evtugyn@kpfu.ru
俄罗斯联邦, Kazan, 420008
I. Stoikov
Butlerov Institute of Chemistry
Email: Gennady.Evtugyn@kpfu.ru
俄罗斯联邦, Kazan, 420008
G. Evtyugin
Butlerov Institute of Chemistry
编辑信件的主要联系方式.
Email: Gennady.Evtugyn@kpfu.ru
俄罗斯联邦, Kazan, 420008
T. Gianik
Butlerov Institute of Chemistry; Comenius University in Bratislava
Email: Gennady.Evtugyn@kpfu.ru
俄罗斯联邦, Kazan, 420008; Bratislava, 842 48
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