Surfactant-Assisted Voltammetric Determination of Olanzapine at Amine Functionalized TiO2/Multi-Walled Carbon Nanotubes Nanocomposite
- Авторы: Majid Arvand 1, Akram Pourhabib 2
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Учреждения:
- Electroanalytical Chemistry Laboratory, Faculty of Chemistry, University of Guilan
- Research House of Professor Reza, Education Guilan
- Выпуск: Том 74, № 11 (2019)
- Страницы: 1096-1103
- Раздел: Articles
- URL: https://journals.rcsi.science/1061-9348/article/view/183335
- DOI: https://doi.org/10.1134/S1061934819110030
- ID: 183335
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Аннотация
This paper describes the development and utilization of a new nanocomposite consisting of amine-functionalized TiO2/multi-walled carbon nanotubes and sodium dodecylsulfate for glassy carbon electrode modification. The nanocomposite was characterized by Fourier transform infrared spectroscopy, transmission electron microscopy and scanning electron microscopy. The modified electrode was used for electrochemical characterization of olanzapine (OLZ). The efficiency of modified electrode for electrocatalytic oxidation of OLZ was studied by cyclic voltammetry and square wave voltammetry in phosphate buffer solution (pH 7.0). Using square wave voltammetry, the prepared sensor showed good sensitivity and selectivity with low overpotential for the determination of OLZ in the ranges from 0.05 to 0.1 and 0.1 to 10 μM, with a detection limit of 8 nM. The proposed method was employed for the determination of OLZ in tablet and blood serum samples without any pretreatment steps.
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Об авторах
Majid Arvand
Electroanalytical Chemistry Laboratory, Faculty of Chemistry, University of Guilan
Автор, ответственный за переписку.
Email: arvand@guilan.ac.ir
Иран, Rasht
Akram Pourhabib
Research House of Professor Reza, Education Guilan
Email: arvand@guilan.ac.ir
Иран, Rasht