A comparison of electrospray tandem mass spectra of some sialic acid derivatives: Ion trap and high resolution QqToF mass spectrometers
- Авторы: Chizhov A.1, Shpirt A.1, Savel’eva N.1,2, Kononov L.1
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Учреждения:
- Zelinsky Institute of Organic Chemistry
- Higher Chemical College
- Выпуск: Том 71, № 14 (2016)
- Страницы: 1392-1396
- Раздел: Articles
- URL: https://journals.rcsi.science/1061-9348/article/view/182263
- DOI: https://doi.org/10.1134/S1061934816140045
- ID: 182263
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Аннотация
Using O-acetyl-N-acyl derivatives of O-methyl sialoside methyl esters, it was shown that an ion trap and a hybrid analyzer (linear quadrupole–time-of-flight analyzer, reflectron) give comparable, though not identical secondary mass spectra for the [M + Na]+ and [M + K]+ ions. A parallel use of an ion trap and a hybrid QqToF instrument gives information about the fragmentation pathways of ions of sialic acid derivatives under collisional activation. In this case, the sequence of fragmentation may be established using an ion trap, whereas a QqToF instrument offers a possibility of revealing the elemental composition of fragment ions quickly and unequivocally.
Об авторах
A. Chizhov
Zelinsky Institute of Organic Chemistry
Автор, ответственный за переписку.
Email: chizhov@ioc.ac.ru
Россия, Moscow, 119991
A. Shpirt
Zelinsky Institute of Organic Chemistry
Email: chizhov@ioc.ac.ru
Россия, Moscow, 119991
N. Savel’eva
Zelinsky Institute of Organic Chemistry; Higher Chemical College
Email: chizhov@ioc.ac.ru
Россия, Moscow, 119991; Moscow, 125047
L. Kononov
Zelinsky Institute of Organic Chemistry
Email: chizhov@ioc.ac.ru
Россия, Moscow, 119991