Simultaneous Determination of Succinic Acid and Water-Soluble Vitamins by Ion-Pair High-Performance Liquid Chromatography
- Autores: Leonov K.1, Pustovoitov A.2, Vishenkova D.1
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Afiliações:
- Institute of Natural Resources
- OOO “Sibtest,”
- Edição: Volume 73, Nº 4 (2018)
- Páginas: 358-363
- Seção: Articles
- URL: https://journals.rcsi.science/1061-9348/article/view/183000
- DOI: https://doi.org/10.1134/S1061934818040068
- ID: 183000
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Resumo
A procedure is proposed for the determination of succinic acid, riboxin, nicotinamide, and riboflavin by ion-pair HPLC with UV detection. Owing to the addition of an ion-pair modifier to the mobile phase and the selection of gradient elution conditions, the optimal retention and resolution of peaks of the components to be determined are achieved. Specificity, linearity, accuracy, and precision of the developed procedure are proved on an example of the determination of active substances in the Cerebronorm® preparation.
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Sobre autores
K. Leonov
Institute of Natural Resources
Autor responsável pela correspondência
Email: leonov_k90@mail.ru
Rússia, Tomsk, 634034
A. Pustovoitov
OOO “Sibtest,”
Email: leonov_k90@mail.ru
Rússia, Tomsk, 634034
D. Vishenkova
Institute of Natural Resources
Email: leonov_k90@mail.ru
Rússia, Tomsk, 634034