Determination of flunixin by sensitized terbium fluorescence in the presence of surfactant micelles
- Autores: Smirnova T.1, Shtykov S.1, Zhelobitskaya E.1, Safarova M.2
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Afiliações:
- Institute of Chemistry
- OOO NITA-FARM
- Edição: Volume 72, Nº 5 (2017)
- Páginas: 562-566
- Seção: Articles
- URL: https://journals.rcsi.science/1061-9348/article/view/182456
- DOI: https://doi.org/10.1134/S1061934817050124
- ID: 182456
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Resumo
The effect of surfactant micelles and the second ligand on the efficiency of energy transfer in the Tb3+–flunixin complex was studied. The fluorescence intensity of the Tb3+–flunixin complex was shown to 100-fold increase in the presence of Tween 80 micelles and the second trioctylphosphine oxide ligand. A procedure for the fluorimetric determination of flunixin in the Flunex drug product (NITA-FARM, Saratov, Russia) was developed. The linearity range of the calibration curve was from 1 × 10–7 to 1 × 10–4 M, r2 = 0.991, and the limit of detection was 4 × 10–8 M (3σ).
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Sobre autores
T. Smirnova
Institute of Chemistry
Autor responsável pela correspondência
Email: smirnovatd@mail.ru
Rússia, Saratov, 410012
S. Shtykov
Institute of Chemistry
Email: smirnovatd@mail.ru
Rússia, Saratov, 410012
E. Zhelobitskaya
Institute of Chemistry
Email: smirnovatd@mail.ru
Rússia, Saratov, 410012
M. Safarova
OOO NITA-FARM
Email: smirnovatd@mail.ru
Rússia, Saratov, 410030
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