Selective Voltammetric and Flow-Injection Determination of Guanosine and Adenosine at a Glassy Carbon Electrode Modified with a Ruthenium Hexachlororuthenate Film
- Авторлар: Shaidarova L.1, Gedmina A.1, Demina V.1, Chelnokova I.1, Budnikov H.1
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Мекемелер:
- Butlerov Institute of Chemistry
- Шығарылым: Том 73, № 4 (2018)
- Беттер: 390-398
- Бөлім: Articles
- URL: https://journals.rcsi.science/1061-9348/article/view/183010
- DOI: https://doi.org/10.1134/S1061934818040111
- ID: 183010
Дәйексөз келтіру
Аннотация
An inorganic film of ruthenium hexachlororuthenate (RuRuCl6), deposited on the surface of a glassy carbon electrode, exhibits electrocatalytic activity in the oxidation of purine nucleosides, such as guanosine and adenosine. Appropriate operating conditions are found for fabricating a polymer film on the surface of glassy carbon and for recording the maximum electrocatalytic current for the modified electrode. A method for the selective voltammetric determination of guanosine and adenosine in their simultaneous presence at an electrode modified by a RuRuCl6 film is developed. A procedure is proposed for the amperometric detection of purine nucleosides with this modified electrode under the conditions of flow-injection analysis. The linear dependence of the analytical signal on the concentration of guanosine and adenosine is observed up to 5 × 10–6 M in the stationary mode and up to 5 × 10–7 M in the flow system. The proposed method for the selective determination of guanosine and adenosine was tested in the analysis of human urine.
Авторлар туралы
L. Shaidarova
Butlerov Institute of Chemistry
Хат алмасуға жауапты Автор.
Email: larisashaidarova@mail.ru
Ресей, Kazan, 420008
A. Gedmina
Butlerov Institute of Chemistry
Email: larisashaidarova@mail.ru
Ресей, Kazan, 420008
V. Demina
Butlerov Institute of Chemistry
Email: larisashaidarova@mail.ru
Ресей, Kazan, 420008
I. Chelnokova
Butlerov Institute of Chemistry
Email: larisashaidarova@mail.ru
Ресей, Kazan, 420008
H. Budnikov
Butlerov Institute of Chemistry
Email: larisashaidarova@mail.ru
Ресей, Kazan, 420008