Evaluation of the Possibility of Volatile Organic Compounds Determination in Exhaled Air by Gas Chromatography for the Noninvasive Diagnostics of Lung Cancer
- Authors: Gashimova E.M.1, Temerdashev A.Z.1, Porkhanov V.A.2, Polyakov I.S.2, Perunov D.V.2, Azaryan A.A.1, Dmitrieva E.V.1
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Affiliations:
- Kuban State University
- Research Institute—Regional Clinical Hospital No. 1 named after Professor S.V. Ochapovsky
- Issue: Vol 74, No 5 (2019)
- Pages: 472-479
- Section: Articles
- URL: https://journals.rcsi.science/1061-9348/article/view/183210
- DOI: https://doi.org/10.1134/S1061934819050034
- ID: 183210
Cite item
Abstract
The possibility of determining volatile organic compounds contained in exhaled air by concentrating them in sorption tubes, two-stage thermal desorption, and gas-chromatographic determination with a flame-ionization detector on various chromatographic columns was studied. It has been established that Tenax TA is an optimal sorbent for the preconcentration, and the highest separation efficiency is achieved on a PLOT CP-Porabond-Q column. The preconcentration of analytes with no breakthrough was achieved upon passing a 0.5-L sample through a sorbent at a rate of 200 mL/min.
About the authors
E. M. Gashimova
Kuban State University
Author for correspondence.
Email: elina.gashimova@yandex.ru
Russian Federation, Krasnodar, 350040
A. Z. Temerdashev
Kuban State University
Email: elina.gashimova@yandex.ru
Russian Federation, Krasnodar, 350040
V. A. Porkhanov
Research Institute—Regional Clinical Hospital No. 1 named after Professor S.V. Ochapovsky
Email: elina.gashimova@yandex.ru
Russian Federation, Krasnodar, 350086
I. S. Polyakov
Research Institute—Regional Clinical Hospital No. 1 named after Professor S.V. Ochapovsky
Email: elina.gashimova@yandex.ru
Russian Federation, Krasnodar, 350086
D. V. Perunov
Research Institute—Regional Clinical Hospital No. 1 named after Professor S.V. Ochapovsky
Email: elina.gashimova@yandex.ru
Russian Federation, Krasnodar, 350086
A. A. Azaryan
Kuban State University
Email: elina.gashimova@yandex.ru
Russian Federation, Krasnodar, 350040
E. V. Dmitrieva
Kuban State University
Email: elina.gashimova@yandex.ru
Russian Federation, Krasnodar, 350040