An Enantioselective Voltammetric Sensor System Based on Glassy Carbon Electrodes Modified by Polyarylenephthalide Composites with α-, β-, and γ-Cyclodextrins for Recognizing D- and L-Tryptophans

Abstract

We developed an enantioselective voltammetric sensor system based on glassy carbon electrodes modified by polyarylenephthalide composites with α-, β-, and γ-cyclodextrins for the selective recognition and determination of tryptophan (Trp) enantiomers. The electrochemical characteristics of the electrodes and surface morphology were studied by cyclic voltammetry, electrochemical impedance spectroscopy, and atomic force microscopy. The proposed sensor system with recording voltammograms by three electrodes and the chemometric processing of the data using principal component analysis and projections to latent structures discriminant analysis was used to recognize tryptophan enantiomers in food additives and to determine their manufacturer.