New Chiral Stationary Phases: Preparation, Properties, and Applications in Gas Chromatography

Abstract

This review surveys chiral chromatographic phases, their properties and preparation methods, and applicability to gas chromatography. New chiral chromatographic phases based on cyclodextrins, ionic liquids, liquid crystals, cyclofructans, etc., are considered. Chiral stationary phases obtained with the use of nanomaterials (structured polymers, including those with molecular traps and molecular imprints, organometallic structures with different types of chirality, and chiral stationary phases based on supramolecular self-assembling structures with induced chirality) are considered separately. It is shown that the chiral phases based on nanomaterials exhibit high enantioselectivity for difficult-to-separate racemates.