Enzymeless determination of cholesterol using gold and silver nanoparticles as electrocatalysts
- Authors: Okhokhonin A.V.1, Saraeva S.Y.1, Matern A.I.1, Kozitsina A.N.1
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Affiliations:
- Institute of Chemical Engineering
- Issue: Vol 72, No 4 (2017)
- Pages: 354-361
- Section: Articles
- URL: https://journals.rcsi.science/1061-9348/article/view/182365
- DOI: https://doi.org/10.1134/S1061934817040116
- ID: 182365
Cite item
Abstract
We present the results of synthesis and study of the electrocatalytic activity of gold and silver nanoparticles of different composition (individual metals, core–shell particles, nanoalloys, and particles synthesized electrochemically), immobilized on the surface of a glassy carbon electrode, with respect to cholesterol. A surfactant (cetyltrimethylammonium bromide) is selected to create an aqueous–organic emulsion of cholesterol. It is demonstrated that nanoparticles with a gold core and a silver shell with the regression equation of I = 1.4 × 10–5cchol + 5.8 × 10–5 (R2 = 0.97) and silver nanoparticles synthesized electrochemically with the regression equation of I = 1.0 × 10–5cchol + 3.0 × 10–4 (R2 = 0.95) possess optimal electrocatalytic characteristics.
Keywords
About the authors
A. V. Okhokhonin
Institute of Chemical Engineering
Author for correspondence.
Email: a.v.ohohonin@urfu.ru
Russian Federation, Yekaterinburg, 620062
S. Yu. Saraeva
Institute of Chemical Engineering
Email: a.v.ohohonin@urfu.ru
Russian Federation, Yekaterinburg, 620062
A. I. Matern
Institute of Chemical Engineering
Email: a.v.ohohonin@urfu.ru
Russian Federation, Yekaterinburg, 620062
A. N. Kozitsina
Institute of Chemical Engineering
Email: a.v.ohohonin@urfu.ru
Russian Federation, Yekaterinburg, 620062