Amperometric detection of hydroxypurines at an electrode modified with a composite based on mixed-valence ruthenium and cobalt oxides in flow injection analysis
- Authors: Shaidarova L.G.1, Chelnokova I.A.1, Il’ina M.A.1, Gedmina A.V.1, Budnikov H.C.1
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Affiliations:
- Butlerov Institute of Chemistry
- Issue: Vol 72, No 1 (2017)
- Pages: 107-112
- Section: Articles
- URL: https://journals.rcsi.science/1061-9348/article/view/182290
- DOI: https://doi.org/10.1134/S1061934817010105
- ID: 182290
Cite item
Abstract
A composite material based on mixed-valence ruthenium and cobalt oxides, electrodeposited on the surface of a screen printed electrode, exhibits high catalytic activity in the electrooxidation of uric acid, xanthine, and hypoxanthine. Catalysis manifests itself as a decrease in the substrate oxidation overvoltage and an increase in current at the potential of modifier oxidation. A method is proposed for the simultaneous amperometric detection of two-component systems uric acid–xanthine, xanthine–hypoxanthine, and uric acid–hypoxanthine using a screen printed electrode with two working electrodes modified by this composite. The dependence of the analytical signal on the concentration of analytes is linear in the range 5 × 10–8 to 5 × 10–3 M for uric acid and xanthine and from 5 × 10–7 to 5 × 10–3 M for hypoxanthine.
About the authors
L. G. Shaidarova
Butlerov Institute of Chemistry
Author for correspondence.
Email: larisashaidarova@mail.ru
Russian Federation, Kazan, 420008
I. A. Chelnokova
Butlerov Institute of Chemistry
Email: larisashaidarova@mail.ru
Russian Federation, Kazan, 420008
M. A. Il’ina
Butlerov Institute of Chemistry
Email: larisashaidarova@mail.ru
Russian Federation, Kazan, 420008
A. V. Gedmina
Butlerov Institute of Chemistry
Email: larisashaidarova@mail.ru
Russian Federation, Kazan, 420008
H. C. Budnikov
Butlerov Institute of Chemistry
Email: larisashaidarova@mail.ru
Russian Federation, Kazan, 420008
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