Email this article Mitochondrial disfunction in Friedreich disease: biochemical and cytochemical aspects
- Authors: Ershova M.V.1,2, Illarioshkin S.N.1,2, Sukhorukov V.S.1,2, Klushnikov S.A.1,2, Phedorova T.N.1,2, Ivanova-Smolenskaya I.A.1,2
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Affiliations:
- Research Institute of Neurology, Russian Academy of Medical Sciences
- Research Institute of Pediatrics and Pediatric Surgery, Ministry of Health of Russia
- Issue: Vol XXXIV, No 3-4 (2002)
- Pages: 5-11
- Section: Original article
- URL: https://journals.rcsi.science/1027-4898/article/view/89853
- DOI: https://doi.org/10.17816/nb89853
- ID: 89853
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Abstract
Some lesions were revealed in the system of oxidation mitochondrial phosphorylation in Fredreich disease, as well as their correlation with the disease course at its different clinical variants. A vivid tendency has been traced to normalization of these cytochemical indices after single treatment by medicines, stabilizing mitochondrial functions.
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##article.viewOnOriginalSite##About the authors
M. V. Ershova
Research Institute of Neurology, Russian Academy of Medical Sciences; Research Institute of Pediatrics and Pediatric Surgery, Ministry of Health of Russia
Author for correspondence.
Email: info@eco-vector.com
Russian Federation, Moscow; Moscow
S. N. Illarioshkin
Research Institute of Neurology, Russian Academy of Medical Sciences; Research Institute of Pediatrics and Pediatric Surgery, Ministry of Health of Russia
Email: info@eco-vector.com
Russian Federation, Moscow; Moscow
V. S. Sukhorukov
Research Institute of Neurology, Russian Academy of Medical Sciences; Research Institute of Pediatrics and Pediatric Surgery, Ministry of Health of Russia
Email: info@eco-vector.com
Russian Federation, Moscow; Moscow
S. A. Klushnikov
Research Institute of Neurology, Russian Academy of Medical Sciences; Research Institute of Pediatrics and Pediatric Surgery, Ministry of Health of Russia
Email: info@eco-vector.com
Russian Federation, Moscow; Moscow
T. N. Phedorova
Research Institute of Neurology, Russian Academy of Medical Sciences; Research Institute of Pediatrics and Pediatric Surgery, Ministry of Health of Russia
Email: info@eco-vector.com
Russian Federation, Moscow; Moscow
I. A. Ivanova-Smolenskaya
Research Institute of Neurology, Russian Academy of Medical Sciences; Research Institute of Pediatrics and Pediatric Surgery, Ministry of Health of Russia
Email: info@eco-vector.com
Russian Federation, Moscow; Moscow
References
- Иллариошкин С.Н., Друзина Е.Б., Багиева Г.Х. и др. // Журн. неврол. и психиатр. им. С.С. Корсакова. — 1999. — №8.— С. 31—34.
- Нарциссов Р.П. // Педиатрия. — 1998 — № 4. — С. 101—105.
- Нарциссов Р.П. // Арх. анатом. гистол. и эмбриол. — 1969. — № 5. — С. 85—91.
- Barhean А. // Can. J. Neurol. Sci. — 1984. — Vol. 11. — Р. 646—660.
- Bidichandani S.I., Ashizawa T., Patel P.I. // Am. J. Hum. Genet. — 1997. — Vol. 60. — P. 1251—1256.
- Campuzano V., Montermini L., Koutnikova H. et al. // Science. — 1996. — Vol. 271. — P. 1423—1427.
- Chamberlain S., Shaw J., Rowland A.., Wallis J. et al. // Nature. — 1988. — Vol. 334. — P. 248—250.
- Cossee M., Durr A., Cavalcanti F. et al. // Ann. Neurol. — 1999. — Vol. 45. — P. 200—206.
- Dnizina E., Illarioshkin S., Ovchinnikov I. et al. // Med. Genet. — 1997. — Vol. 9 (SuppL). — P. 50.
- Durr A., Cossee M., Agid Y. et al. // N. Engl. J. Med. — 1996. — Vol. 335. — P. 1169—1175.
- Filla A., De Michele G. // J. Neurol. — 1992. — Vol. 239. — P. 351—353.
- Pilla A., De Michele G., Cavalcanti F. et al. // Am. J. Hum. Genet. — 1996. — Vol. 59. — P. 554—560.
- Geoffrey G., Barbeau A., Breton G. et al. // Can. J. Neurol. Sci. — 1976. — Vol. 3. — P. 279—286.
- Gray J. V., Johnson K.J. //Nat Gen. — 1997. —Vol. 16. — P. 323—328.
- Harcling A.E. // Brain. — 1981. — Vol. 104. — P. 598—620.
- Harding A.E. The hereditary ataxias and related disorders. Edinburgh: Churchill Livingstone, 1984.
- Wariosbkm S.N., Bagieva G.Kh., Klyushnikov S.A. et al. //Eur. J. Neurol. — 2000. — Vol. 7. — P. 535—540.
- Lodi R., Cooper J., Bradley J. et al. // Proc. Nat. Acad. Sci. USA. — 1999. — Vol. 96. — P. 11492—11495.
- Pandolfo M. // Mov. Disord. — 2001. — Vol. 16. — P. 815—821.
- Pandolfo M. // Neuromus Dis. —1998. — Vol. 8.— p. 409—415.
- Puccio H., Koenig M. // Hum. Mol. Gen. 2000. — Vol. 9. — P. 887—892.
- Rotig A., De Lonlay P., Chretien D. et al. // Nat. Genet. 1997. — Vol. 17. — P. 215—217.
- Rotig A., Lonlay P., Chretien D. et al. // Nat. Genet. — 1997. — Vol. 17. — P 215—218.
- Schniz J.B., Dehmer T., Schols L. et al. // Neurology. — 2000. — Vol. 55. — P. 1719—1721.
- Sherer T., Greenamyre J.T. // Neurology. — 2000. — Vol. 55. — P. 1601—1602.
- Vorgerd M., Schols L., Hardt C. et al. // Neuromusc. Disord. —2000. — Vol. 10. — P. 430—435.
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