A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia (Proc. Natl. Acad. Sci. USA. — 1999. — Nov. 9. — Vol. 96. — P. 13496 — 13500: англ.)

J. Yrjanheikki; Yrjanheikki J.; T. Tikka; Tikka T.; R. Keinanen; Keinanen R.; G. Goldsteins; Goldsteins G.; P. H. Chan; Chan P. H.; J. Koistinaho; Koistinaho J.

doi:10.17816/nb79500

A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia (Proc. Natl. Acad. Sci. USA. — 1999. — Nov. 9. — Vol. 96. — P. 13496 — 13500: англ.)

Authors: Yrjanheikki J.¹, Tikka T.¹, Keinanen R.¹, Goldsteins G.¹, Chan P.H.¹, Koistinaho J.¹
Affiliations:
1. Stanford University School of Medicine
Issue: Vol XXXII, No 3-4 (2000)
Pages: 76-76
Section: Articles
URL: https://journals.rcsi.science/1027-4898/article/view/79500
DOI: https://doi.org/10.17816/nb79500
ID: 79500

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Abstract

One of the reasons for the insufficient effectiveness of treatment of acute ischemic stroke may be secondary inflammation of the brain tissue, which, according to the results of modern studies, significantly worsens the consequences and outcome of the disease.