Email this article Neurorehabilitation on the genome level: theoretical principles and experimental prerequisites
- Authors: Cherepnev G.V.1, Zulkarneeva Z.R.2
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Affiliations:
- Kazan State Medical University
- Kazan city neuropsychiatric hospital named after V. M. Bekhtereva
- Issue: Vol XXVII, No 1-2 (1995)
- Pages: 27-30
- Section: Articles
- URL: https://journals.rcsi.science/1027-4898/article/view/78575
- DOI: https://doi.org/10.17816/nb78575
- ID: 78575
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Abstract
The mechanisms of control of genetic homeostasis of neurons and their role in the etiopathogenesis of some neurodegenerative and mental diseases and aging are briefly considered. For the purpose of possible prevention and (or) compensation of these disorders, it is proposed to pharmacologically modulate the activity of systems that ensure the stability of the cell genome.
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##article.viewOnOriginalSite##About the authors
G. V. Cherepnev
Kazan State Medical University
Author for correspondence.
Email: info@eco-vector.com
Department of Clinical Immunology and Allergology
Russian Federation, KazanZ. R. Zulkarneeva
Kazan city neuropsychiatric hospital named after V. M. Bekhtereva
Email: info@eco-vector.com
head of the department of social and psychological assistance
Russian Federation, KazanReferences
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Fig. 1. Effect of xymedon and para-aminobenzoic acid on reparative DNA synthesis in lymphocytes of CBA x C57B1 mice
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Fig. 2. Inhibitor of DNA polymerase ß 2 ', 3' dideoxythymidine cancels xymedon-mediated enhancement of reparative DNA synthesis
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