Astroglia and its role in epileptogenesis

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Abstract

Modern ideas about the functional significance of astroglia in the formation of convulsive activity of the brain are outlined. Modern data on astrocyte metabolism, its role in the metabolism of neurotransmitters, peptides, neurotrophic factors in various receptions are presented. Particular attention is paid to the role of astroglia in the metabolism of the excitatory amino acid glutamate. Modern concepts of astroglial mechanisms of epileptogenesis are considered.

About the authors

I. A. Zavalishin

Research Institute of Neurology (Director - Academician of the Russian Academy of Medical Sciences N.V. Vereshchagin) RAMS

Author for correspondence.
Email: info@eco-vector.com
Russian Federation, Moscow

М. N. Zakharova

Research Institute of Neurology (Director - Academician of the Russian Academy of Medical Sciences N.V. Vereshchagin) RAMS

Email: info@eco-vector.com
Russian Federation, Moscow

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Copyright (c) 1993 Zavalishin I.A., Zakharova М.N.

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