Insulators can disrupt weak transcription derived from the white gene enhancer in Drosophila transgenic lines


如何引用文章

全文:

开放存取 开放存取
受限制的访问 ##reader.subscriptionAccessGranted##
受限制的访问 订阅存取

详细

Increasing evidence suggests that noncoding RNA transcribed from the enhancers play an important role in the regulation of gene transcription. Insulators are the regulatory elements that limit the activity of enhancers and form independent transcriptional domains. Using a transgenic lines, we show that the Fab-7 insulator of the bithorax complex and the MDG4 (gypsy) insulator are able to disrupt weak transcription derived from the enhancer regulating the white gene expression in the eyes. The ability of insulators to disrupt weak transcription may play a role in the enhancer-blocking activity.

作者简介

O. Kyrchanova

Institute of Gene Biology

编辑信件的主要联系方式.
Email: olgina73@gmail.com
俄罗斯联邦, Moscow, 119334

N. Postika

Institute of Gene Biology

Email: olgina73@gmail.com
俄罗斯联邦, Moscow, 119334

A. Parshikov

Institute of Gene Biology

Email: olgina73@gmail.com
俄罗斯联邦, Moscow, 119334

P. Georgiev

Institute of Gene Biology

Email: olgina73@gmail.com
俄罗斯联邦, Moscow, 119334

补充文件

附件文件
动作
1. JATS XML

版权所有 © Pleiades Publishing, Inc., 2016