Mutation induction in the mouse and human germline
- Авторлар: Dubrova Y.1,2
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Мекемелер:
- Department of Genetics
- Vavilov Institute of General Genetics
- Шығарылым: Том 52, № 1 (2016)
- Беттер: 17-28
- Бөлім: Reviews and Theoretical Articles
- URL: https://journals.rcsi.science/1022-7954/article/view/187630
- DOI: https://doi.org/10.1134/S1022795416010038
- ID: 187630
Дәйексөз келтіру
Аннотация
The review describes the effects of exposure to mutagens on mutation induction in human and mouse germlines. The results of studies that evaluated inductions of mutations in human families subjected to irradiation are presented and discussed. The effects of exposure to mutagens on mutation induction in the mouse germline are also considered. We analyze and discuss the recent data on the genome-wide effects of irradiation on mutation induction in the mouse germline obtained by next-generation sequencing and comparative genome hybridization.
Негізгі сөздер
Авторлар туралы
Yu. Dubrova
Department of Genetics; Vavilov Institute of General Genetics
Хат алмасуға жауапты Автор.
Email: yed2@le.ac.uk
Ұлыбритания, Leicester, LEI 7RH; Moscow, 119991