Mutation induction in the mouse and human germline
- 作者: Dubrova Y.1,2
-
隶属关系:
- Department of Genetics
- Vavilov Institute of General Genetics
- 期: 卷 52, 编号 1 (2016)
- 页面: 17-28
- 栏目: Reviews and Theoretical Articles
- URL: https://journals.rcsi.science/1022-7954/article/view/187630
- DOI: https://doi.org/10.1134/S1022795416010038
- ID: 187630
如何引用文章
详细
The review describes the effects of exposure to mutagens on mutation induction in human and mouse germlines. The results of studies that evaluated inductions of mutations in human families subjected to irradiation are presented and discussed. The effects of exposure to mutagens on mutation induction in the mouse germline are also considered. We analyze and discuss the recent data on the genome-wide effects of irradiation on mutation induction in the mouse germline obtained by next-generation sequencing and comparative genome hybridization.
关键词
作者简介
Yu. Dubrova
Department of Genetics; Vavilov Institute of General Genetics
编辑信件的主要联系方式.
Email: yed2@le.ac.uk
英国, Leicester, LEI 7RH; Moscow, 119991